An environmentally safe approach for the facile synthesis of anti-mutagenic fluorescent quantum dots: Property investigation and the development of novel antimicrobial applications

نویسندگان

چکیده

Quantum dots as nanocrystals of semiconductor materials are synthesized with different methods. The green synthesis fluorescent quantum using natural stabilizing agents has attracted much attention. This research aims to study the ability Teucrium polium L. extract synthesize silver (AgQDs). AgQDs was proved UV–Visible spectrophotometer, Fourier Transform Infrared spectroscopy (FTIR), X-Ray Diffraction (XRD), Transmission Electron Microscopy (TEM), Scanning (SEM), Energy-Dispersive X-ray (EDX), Photoluminescence (PL) analysis, and Dynamic Light Scattering (DLS). According findings, shape spherical, maximum abundance particle size distribution between 3 5 nm. Thereupon, antimicrobial, anti-mutagenicity, anticancer, antioxidant activities were evaluated distinguish biological features AgQDs. Gram-positive bacteria (S. epidermidis, MIC: 31.25 μg/ml) fungi (C. albicans, most susceptible Moreover, solution had higher antimicrobial activity than AgNO3. Ames test demonstrated that have considerable anti-mutagenic (% mutagenicity inhibition greater 40) not mutagenic. anticancer distinguished MTT brine shrimp lethality (BSL) assays. analysis indicated a strong potential for cytotoxicity (BSL: LC50 = 2.4 μg/ml, MTT: IC50 0.8 μg/ml). Further, used bioimaging human ovarian OVCAR3 cells, their biocompatibility remarkable. In DPPH assay, displayed high (89.9% inhibition). Using coat develop antibacterial revealed significant against C. albicans S. epidermidis strains. Our results indicate T. is promising source synthesizing Due potent bioactivities AgQDs, they can be in medicine industry.

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ژورنال

عنوان ژورنال: Arabian Journal of Chemistry

سال: 2023

ISSN: ['1878-5379', '1878-5352']

DOI: https://doi.org/10.1016/j.arabjc.2023.104811